Dopa-Responsive Dystonia

Quick Facts

  • Dopa-responsive dystonia (DRD) is a broad term used to describe forms of dystonia that respond to a medication called levodopa, which is a synthetic form of a brain chemical called dopamine.
  • DRD includes heredity forms that are characterized by progressive difficulty walking.
  • Symptoms of DRD may be similar to those of early onset generalized dystonia and typically begin in the legs.
  • Symptoms of DRD are often worse later in the day and may increase with exertion.
  • DRD can usually be treated effectively with a drug called levodopa, and most often a combination of levodopa and carbidopa.
  • In many cases, full physical functionality--including walking, running, speaking, writing--is restored or preserved with levodopa therapy.

Click here for more information.

Accelerating Research & Inspiring Hope

The Dystonia Medical Research Foundation (DMRF) has served the dystonia community since 1976. Join us in our global effort to find a cure.