Dopaminergic agents/Dopamine-depleting
agents
Some patients with primary dystonia respond to drugs which
increase the
neurotransmitter dopamine. These drugs are called dopaminergic agents and include Sinemet® (levodopa)
or Parlodel® (bromocriptine). Side effects may include parkinsonism,
hypotension, and depression. Ironically,
however, many patients respond to agents which block or deplete dopamine. Many
of these drugs are such as antipsychotic agents like Clozaril® (clozapine),
Nitoman® (tetrabenazine), or Reserpine®.
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