The DMRF Partners With Tyler's Hope For A Dystonia Cure

The DMRF is partnering with Tyler’s Hope For A Dystonia Cure to advance research on DYT1 dystonia. Rick and Michelle Staab founded Tyler’s Hope shortly after their son Tyler was diagnosed. The mission of the organization is to cure DYT1 dystonia, the form that affects two of their three children.

A generous grant from Tyler’s Hope supported groundbreaking studies including William Dauer, MD’s investigation on the dystonia protein torsinA at Columbia University in New York as well as Pedro Gonzalez-Alegre, MD’s investigation on RNAi as a novel dystonia therapy at the University of Iowa. Tyler’s Hope also supported a DMRF contract with dystonia investigators Cristopher Bragg, PhD and Xandra Breakefield, PhD to develop and screen chemical compounds that impact the disruptive effect of mutated torsinA in cells.

DMRF President Claire Centrella explains, “The DMRF and Tyler’s Hope share the desire to aggressively and strategically pursue the best research toward a cure. It’s fantastic that we are able to work together. We’re so grateful for Tyler's Hope’s partnership.”






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